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HCl API Intermediates Cas 16595-80-5
This product is white or yellowish needle crystal. It is odorless, bitter, soluble in water and stable in acidic aqueous solutions. The temperature of 227 ~ 229 ° C. Specific optical rotation [α] D20 -124 ± 2 ° (C = 0.9, water). This powder is toxic and irritating. It is an alkaline phosphatase inhibitor and is used as an anthelmintic in medicine.
Basic Info.
Category: API
CAS NO: 16595-80-5
EC NO: 240-654-6
Molecular Formula: C11H12N2S•ClH
Molecular Weight: 240.757
Specification: EP/USP/CP
InChI: InChI=1/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
Appearance and traits: white to nearly white crystalline powder
Melting point: 226-231oC
Boiling point: 344.4oC at 760 mmHg
Flash point: 162.1oC
Stability: Stable under normal temperatures and pressures. Light sensitive.
Storage conditions: 0-6oC
Synonyms:
(-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride;
Levamisole Hydrochloride; kw-2-le-t;
Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-;
L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole; (-)-(S)-2,3,5,6-tetrahydro-6-phenylimidazo [2,1-b] thiazole monohydrochloride;
Function:
The finished drug intermediate can be made into a left-handed body of tetraimidazole, and the activity is about 1-2 times that of tetraimidazole (racemic body), but the toxic side effect is low. And the drug may have an inhibitory effect on the microtubule structure of the worm. Levamisole also has immunomodulatory and immune excitatory functions. It has good curative effect on aphids, hookworms, aphids and faecal nematodes.
Molecular Structure:
