Levamisole HCl API Intermediates Cas 16595-80-5

Levamisole HCl API Intermediates Cas 16595-80-5

HCl API Intermediates Cas 16595-80-5
Category: API
CAS NO: 16595-80-5
EC NO: 240-654-6
Molecular Formula: C11H12N2S•ClH
Molecular Weight: 240.757

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Product Details

HCl API Intermediates Cas 16595-80-5

This product is white or yellowish needle crystal. It is odorless, bitter, soluble in water and stable in acidic aqueous solutions. The temperature of 227 ~ 229 ° C. Specific optical rotation [α] D20 -124 ± 2 ° (C = 0.9, water). This powder is toxic and irritating. It is an alkaline phosphatase inhibitor and is used as an anthelmintic in medicine.


Basic Info.

Category: API

CAS NO: 16595-80-5

EC NO:  240-654-6

Molecular Formula: C11H12N2S•ClH

Molecular Weight: 240.757

Specification: EP/USP/CP

InChI: InChI=1/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1

Appearance and traits: white to nearly white crystalline powder

Melting point: 226-231oC

Boiling point: 344.4oC at 760 mmHg

Flash point: 162.1oC

Stability: Stable under normal temperatures and pressures. Light sensitive.

Storage conditions: 0-6oC


Synonyms:

(-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride;

Levamisole Hydrochloride; kw-2-le-t;

Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-;

L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole; (-)-(S)-2,3,5,6-tetrahydro-6-phenylimidazo [2,1-b] thiazole monohydrochloride;


Function:

The finished drug intermediate can be made into a left-handed body of tetraimidazole, and the activity is about 1-2 times that of tetraimidazole (racemic body), but the toxic side effect is low. And the drug may have an inhibitory effect on the microtubule structure of the worm. Levamisole also has immunomodulatory and immune excitatory functions. It has good curative effect on aphids, hookworms, aphids and faecal nematodes.


Molecular Structure:


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