Meclizine HCl API Intermediates Cas 31884-77-2

Meclizine HCl,wholesale Meclizine HCl API Intermediates Cas 31884-77-2

Meclizine is a chemical and an antihistamine. It is a white or light yellow crystalline powder, odorless, almost tasteless, and soluble in water.

Efficacy:

This product is an antagonist of histamine receptor, which can resist the antihypertensive effect caused by histamine and protect the animal death caused by lethal amount of histamine, and has central inhibition and local anesthesia. Its anti-motion sickness and vertigo effects are related to its anticholinergic effects. This product is suitable for skin and mucous membrane allergic diseases. It can also be used for nausea and vomiting caused by radiotherapy and motion sickness. Its effect is far longer than that of diphenhydramine, which can last for 12 to 24 hours.

Category: API

CAS NO:  1104-22-9

EC NO:  214-164-8

Molecular Formula: C25H28Cl2N2

Molecular Weight: 427.4092

Specification:  EP/USP

InChI: InChI=1/C25H27ClN2.ClH/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23;/h2-13,18,25H,14-17,19H2,1H3;1H

Storage: shading, sealed and preserved.

Preparation: meclozine hydrochloride tablets

Synonyms:

meclozine dihydrochloride; Meclizine hydrochloride;

1-[(4-chlorophenyl)(phenyl)methyl]-4-(3-methylbenzyl)piperazine;

1-[(4-chlorophenyl)(phenyl)methyl]-4-(3-methylbenzyl)piperazine dihydrochloride;

1-[(4-chlorophenyl)(phenyl)methyl]-4-(3-methylbenzyl)piperazine hydrochloride (1:1);

Molecular Structure:

Overdose:

Excessive amounts may cause confusion, convulsions, tremors, difficulty breathing, and low blood pressure. If taking the amount of poisoning, gastric lavage and catharsis can be used. When convulsing, you can control the sputum.