Niclosamide API Intermediates Cas 50-65-7
Niclosamide is an ammunicide and a molluscicide, a salicylamide derivative. Its anti-insect mechanism is to inhibit the mitochondrial oxidative phosphorylation process in the cells, and the production of ATP is reduced, which causes the aphid's head section and adjacent segments to deteriorate. The worms are exfoliated from the intestinal wall and excreted with feces. It is not effective against eggs. It also kills snails and schistosoma japonicum cercariae, and kills a wide variety of snails, taenia saginata, taeniasolium, locusts, mites, and cercariae.
Niclosamide is mainly used in agriculture to kill the snails in rice fields (also known as the big bottle snail, apple snail, English Pomacea canaliculata). At the same time, in public health prevention, it is used to kill snails (the intermediate host of schistosomiasis).
Niclosamide can rapidly produce metabolic changes in water for a short period of time. It is also used in commercial fish farming to kill and remove unwanted fish before the fish is replaced with fresh water. Niclosamide is very toxic to fish but has a short half-life in water. After using this fish killer, it takes only a few days to put in new fish.
CAS NO: 50-65-7
EC NO: 200-056-8
Molecular Formula: C13H8Cl2N2O4
Molecular Weight: 327.1196
Storage conditions: placed in a ventilated, cool place, sealed and stored.