Sotalol HCl API Intermediates Cas 959-24-0

Sotalol HCl API Intermediates Cas 959-24-0

Sotalol HCl API Intermediates Cas 959-24-0 is a broad-spectrum antiarrhythmic drug with a class III antiarrhythmic drug that prolongs the action potential duration and has β1, β2 receptor blockade. It has a good effect on supraventricular and ventricular arrhythmia.

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Sotalol HCl API Intermediates Cas 959-24-0

Sotalol is a broad-spectrum antiarrhythmic drug with a class III antiarrhythmic drug that prolongs the action potential duration and has β1, β2 receptor blockade. It has a good effect on supraventricular and ventricular arrhythmia.


Category: API/Cardiovascular agents

CAS NO:  959-24-0

EC NO:  213-496-0

Molecular Formula: C12H20N2O3S•HCl

Molecular Weight: 308.82

Specification: EP

InChI: InChI=1/C12H20N2O3S.ClH/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17;/h4-7,9,12-15H,8H2,1-3H3;1H

Synonyms:

Sotalol Hydrochloride;

4-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide hydrochloride;


Physicochemical properties:

Appearance and traits: white to off-white powder

Melting point: 218-220 ° C

Boiling point: 443.3oC at 760 mmHg

Flash point: 221.9oC

Storage conditions: low temperature ventilation and drying in the warehouse


Molecular Structure:

Use:

This product has oral absorption, rapid action, small myocardial inhibition, safe and effective. Clinically used to treat arrhythmia caused by a variety of reasons, especially for atrial and ventricular premature beats. It can also be used for sinus and supraventricular tachycardia, atrial fibrillation, etc.

Sotalol can also be used for angina to reduce the number of episodes and the amount of nitroglycerin, and to increase exercise tolerance. It can also be used for congestive heart failure and high blood pressure, etc. This product has little side effects, and can cause bradycardia, but does not cause congestive heart failure.

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