Triclabendazole API Intermediates Cas 68786-66-3

Triclabendazole API Intermediates Cas 68786-66-3

Triclobendazole is a benzimidazole anthelmintic that has a strong affinity for tubulin in the structure. It can interfere with the synthesis of cells by affecting the energy transfer function of the cells.

Triclobenazole has a good effect on all three different stages of Fasciola. It is especially effective for early and immature worms, so it is particularly suitable for the treatment of acute and chronic fasciolosis, and is also commonly used for long-term control of Fasciola infection.

Category: API

CAS NO: 68786-66-3

EC NO: /

Molecular Formula: C14H9Cl3N2OS

Molecular Weight: 359.6581

Specification: In-house

InChI: InChI=1/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)

Physicochemical properties

Appearance and traits: white to brown crystalline powder

Density: 1.59 g/cm3

Melting point: 175-176 ° C

Boiling point: 495.9oCat 760 mmHg

Flash point: 253.7oC

Refractive index: 1.724

Stability: Stability

Storage conditions: warehouse low temperature, ventilation, drying

Synonyms:

6-chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole;

6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole;

6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-benzimidazole;

FASINEX;Trichlobendazole;

Molecular Structure:

Pharmacological action: 

Triclobendazole is a new type of imidazole anthelmintic. It has obvious killing effect on various days of liver fluke. This product is less toxic and safe and effective when combined with levamisole and methylpyrimidine.