Triclabendazole API Intermediates Cas 68786-66-3
Triclobendazole is a benzimidazole anthelmintic that has a strong affinity for tubulin in the structure. It can interfere with the synthesis of cells by affecting the energy transfer function of the cells.
Triclobenazole has a good effect on all three different stages of Fasciola. It is especially effective for early and immature worms, so it is particularly suitable for the treatment of acute and chronic fasciolosis, and is also commonly used for long-term control of Fasciola infection.
Category: API
CAS NO: 68786-66-3
EC NO: /
Molecular Formula: C14H9Cl3N2OS
Molecular Weight: 359.6581
Specification: In-house
InChI: InChI=1/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
Physicochemical properties
Appearance and traits: white to brown crystalline powder
Density: 1.59 g/cm3
Melting point: 175-176 ° C
Boiling point: 495.9oCat 760 mmHg
Flash point: 253.7oC
Refractive index: 1.724
Stability: Stability
Storage conditions: warehouse low temperature, ventilation, drying
Synonyms:
6-chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole;
6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole;
6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-benzimidazole;
FASINEX;Trichlobendazole;
Molecular Structure:
Pharmacological action:
Triclobendazole is a new type of imidazole anthelmintic. It has obvious killing effect on various days of liver fluke. This product is less toxic and safe and effective when combined with levamisole and methylpyrimidine.