1-Acetyl-4-(4-hydroxyphenyl)piperazine

1-Acetyl-4-(4-hydroxyphenyl)piperazine

1-Acetyl-4-(4-hydroxyphenyl)piperazine is a ketoconazole intermediate. This intermediate is synthesized from diethanolamine as a starting material by chlorination, cyclization and acylation. The target compound synthesized by this process route has better total product yield than the current process, and the process is simple in operation and low in production cost.

Chat Now

Product Details

1-Acetyl-4-(4-hydroxyphenyl)piperazine is a ketoconazole intermediate. This intermediate is synthesized from diethanolamine as a starting material by chlorination, cyclization and acylation. The target compound synthesized by this process route has better total product yield than the current process, and the process is simple in operation and low in production cost.

Its melting point is 178-180 ° C, and it can be used for the synthesis of the drug ketoconazole, itraconazole.


Category:  Intermediates/Pharmaceutical intermediates

CAS NO: 67914-60-7

EC NO: 267-744-8

Molecular Formula: C12H16N2O2

Molecular Weight: 220.2676

Specification: in-house

Synonyms:

4-(4-acetylpiperazin-4-yl)phenol; 1-Acetyl-4-(4hydroxyphenyl)piperazine;

4-(4-Acetyl-1-piperaino)phenol; Tetraethoxy C methyl propane;

1-[4-(4-hydroxyphenyl)piperazin-1-yl]ethanone; 4-(1-Acetylpiperazin-4-yl)phenol;


Molecular Structure:

 

Previous:No Information Next:N-(Diphenyl) Methyl Piperazine

Inquiry